Increased Neurofibrillary Tangles in the Brains of Older Pedestrians Killed in Traffic Accidents
نویسندگان
چکیده
منابع مشابه
Increased neurofibrillary tangles in the brains of older pedestrians killed in traffic accidents.
BACKGROUND/AIMS Older people are over-represented in pedestrian fatalities, and it has been suggested that the presence of cognitive impairment or dementia in these individuals may contribute to their accidents. Using neuropathological methods, we aimed to compare the prevalence of dementia pathology in fatally injured older pedestrians with similarly aged ambulatory subjects who died from othe...
متن کاملNeurofibrillary Tangles of Aβx-40 in Alzheimer's Disease Brains.
The two pathognomonic lesions in the brain of AD patients are senile plaques and intraneuronal neurofibrillary tangles (NFT). Previous studies have demonstrated that amyloid-β (Aβ) is a component of both senile plaques and NFTs, and have showed that intracellular accumulation of Aβ is toxic for cells and precedes the appearance of extracellular amyloid deposits. Here we report that there are nu...
متن کاملInjuries to pedestrians in road traffic accidents.
Although there have been many reports on injuries to occupants of cars in road traffic accidents, there have been few prospective studies of injuries to pedestrians in such accidents. For this reason a two year prospective study of pedestrians in road traffic accidents in the Oxford region was carried out. The incidence of death in pedestrians was significantly higher than in car occupants or m...
متن کاملBeta amyloid deposition and neurofibrillary tangles spontaneously occur in the brains of captive cheetahs (Acinonyx jubatus).
Alzheimer disease is a dementing disorder characterized pathologically by Aβ deposition, neurofibrillary tangles, and neuronal loss. Although aged animals of many species spontaneously develop Aβ deposits, only 2 species (chimpanzee and wolverine) have been reported to develop Aβ deposits and neurofibrillary tangles in the same individual. Here, the authors demonstrate the spontaneous occurrenc...
متن کاملFactors related to pedestrians mortality following road traffic accidents in Tehran and Alborz Provinces, Iran
Background and aims: This study aimed to investigate the deaths and injuries following pedestrian traffic accidents and factors associated with death of pedestrian in Tehran and Alborz provinces. Methods: In this cross-sectional study all traffic accidents related to pedestrians in Tehran and Alborz provinces reported from March 21, 2013 to March 21, 2014...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Dementia and Geriatric Cognitive Disorders
سال: 2006
ISSN: 1420-8008,1421-9824
DOI: 10.1159/000093066